"Begin with the end in mind" is #2 of Coveys "7 habits of highly effective people". The thrust of the habit is to develop an outcome-oriented mindset in every activity that we engage in. It could be that Covey was significantly influenced by the Apostle Paul who wrote a pretty significant book called '1 Corinthians', for Paul writes 'So we fix our eyes not on what is seen but on what is unseen' (vs 18).
For Paul, amidst the suffering and persecution, the failing body and diminished capacity to hear and see, what he looks to is what is unseen from a human perspective yet very much 'seeable' through the lens of Jesus. Earlier in verse 6, Paul acknowledged that 'God, who said 'let light shine out of darkness' made his light shine in our hearts' as the face of Jesus came into focus. What is it that Paul looks at, when he looks at what is unseen? - it is the face of Jesus. It is the face of the one who confronted him on the road to Damascus; the face of the one who questioned him as to why he was persecuting him, and the one who, as verse 14 reminds us, has been raised to life.
This is why Paul is able to say "We do not lose heart". Its not a matter of mind over matter; rather it's about having faith in the one who not only is in the process of redeeming Creation but is also the one who is working in us and who is transforming us. So let us begin with the end in mind - let us fix our eyes on the one who has been raised to life and who is intent on transforming us into the people we have been redeemed to be.